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KMID : 0613820130230020249
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Journal of Life Science
2013 Volume.23 No. 2 p.249 ~ p.258
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Antioxidative Activity and Chemical Characteristics of Cordycepin-enriched Cordyceps militaris JLM0636 Powder
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Ahn Hee-Young
Cha Jae-Young
Jeong Yong-Kee
Cho Young-Su
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Abstract
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The antioxidative activity and bioactivity of water, ethanol, and methanol extracts from Paecilomyces japonica (PJ), Cordyceps militaris (CM), and cordycepin-enriched C. militaris JLM0636 (CMα) were tested in in vitro experimental models. The PJ water extract showed the highest extraction yield (42.53%). The highest content of phenolic compounds and flavonoids were found in the water extract of PJ, 2.72% and 1.73%, respectively. The major minerals were K, Mg, and Ca. The water extracts of PJ also showed the highest DPPH free radical scavenging activity and reducing power. Linoleic acid peroxidation and antioxidative activities were strong in CMα. The methanol extracts of PJ showed the highest inhibition activity against tyrosinase. Fibriolytic activity was higher in CMα than in CM. These results may provide basic data to understand the biological activities of bioactive materials derived from CMα for the development of functional foods, cosmetics, and antithrombotics.
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KEYWORD
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Paecilomyces japonica, Cordyceps militaris, antioxidative activity, cordycepin, fibriolytic activity
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